Inositol‐requiring 1/X‐box‐binding protein 1 is a regulatory hub that links endoplasmic reticulum homeostasis with innate immunity and metabolism
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Abstract
Inositol‐requiring 1 (IRE1)/X‐box‐binding protein 1 (XBP1)‐mediated signalling represents the most conserved branch of the unfolded protein response. A series of recent studies reveal novel and potentially ancient roles for this pathway in the coordination of metabolic and immune responses.
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10.1002/emmm.201000076 About DOI
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